Lenvat 10 mg Capsule
Prescription Required
Brand Name:
Lenvat 10
Molecule:
LenvatinibStrength:
10 mg
Quantity:
30 Capsules
Form:
Capsule
Packaging Type:
Bottle
Manufacturer/Marketed By:
Natco PharmaCountry of Origin:
India
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Description
Lenvat 10 mg Capsule is a prescription-only medicine that treats certain cancers, including thyroid, kidney, and liver. It contains lenvatinib, which blocks specific proteins that help cancer cells grow and spread throughout the body. By interfering with these proteins, the medicine helps slow down the progression of the disease and may reduce the size of tumors. Natco Pharma Ltd manufactures Lenvat Lenvatinib 10 mg Capsule. Take this medicine strictly under a doctor’s supervision, with regular monitoring during treatment.
Benefits
- Lenvat 10 mg slows down the growth of cancer cells in the thyroid, kidney, and liver.
- Lenvatinib helps to shrink tumors in affected patients.
- Improves overall survival in patients with advanced cancer.
- It can delay the spread of cancer to other body parts.
- It helps relieve symptoms like pain, pressure, or breathing issues related to tumors.
Indications and Usage
Lenvat 10 mg Capsule is used to treat different types of cancer. Doctors prescribe this medicine when cancer cannot be removed by surgery or has spread to other parts of the body.
It is used to treat:
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Thyroid Cancer
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For adults with differentiated thyroid cancer that is progressive (getting worse), and does not respond to radioactive iodine therapy.
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Kidney Cancer (Renal Cell Carcinoma)
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Used with another medicine called everolimus to treat advanced kidney cancer in people who have already tried one treatment.
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Liver Cancer (Hepatocellular Carcinoma)
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Used as a first-line treatment for unresectable liver cancer (cancer that cannot be removed by surgery).
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How it Works
Lenvat 10 mg Capsule contains lenvatinib, a medicine in the tyrosine kinase inhibitor (TKI) group.
What does it do in your body?
- Some cancers grow because of special proteins that tell cancer cells to grow, spread, and make blood vessels.
- These blood vessels bring food and oxygen to the cancer, helping it grow faster.
- Lenvatinib 10 mg blocks these signals, so the cancer cannot grow easily.
What happens when Lenvat 10 mg capsule works?
- It stops the cancer cells from growing.
- It blocks new blood vessels that feed the cancer.
- It helps cancer cells die.
- It can shrink the tumor or stop it from getting bigger.
Which proteins does it block?
Lenvatinib blocks several proteins that are very active in cancer:
- VEGFR (vascular endothelial growth factor receptor)
- FGFR (fibroblast growth factor receptor)
- PDGFR (platelet-derived growth factor receptor)
- RET and KIT (other proteins that help cancer grow)
By blocking these, Lenvat Lenvatinib 10 mg capsules slow or stop the cancer from growing.
Dosage & Administration
Recommended Dosage of Lenvat 10 mg Capsule
- The usual starting dose is 10 mg once per day.
- The dose may change based on:
- Type of cancer
- Body weight
- How your body reacts to the medicine
- Your treating physician must determine the prescribed dosage based on your condition.
How to Take It
- Swallow the capsule whole with a glass of water.
- Do not crush, chew, or open the capsule.
- If you have trouble swallowing, your doctor might tell you how to mix it with water or juice.
Timing
- Take the capsule at the same time every day.
- You can take it with or without food.
Frequency
- The standard dosage is one capsule (10 mg) daily, unless otherwise directed by your doctor.
Missed Dose
- If you forget to take your medicine:
- Take it as soon as you remember.
- If it’s almost time for the next dose, skip the missed one.
- Do not take two doses at the same time.
Overdose Warning
Taking too much of Lenvat 10 mg can be dangerous.
You might get:
- Very high blood pressure
- Severe bleeding
- Liver problems
- Serious side effects
If you take too much by mistake, go to the hospital or call your doctor immediately.
Strengths & Substitutes
| Strength | Alternative Options | ||
| 4 mg | Lenvima 4 mg Capsule | Lenvakast 4mg Capsule | Lenvaxen 4mg Capsule |
| 10 mg | Lenvima 10 mg Capsule | Lenvakast 10 mg Capsule | Lenvaxen 10 mg Capsule |
Side Effects
Common Side Effects of Lenvat 10 mg Capsule:
- High blood pressure
- Diarrhea
- Loss of appetite
- Weight loss
- Headache
- Fatigue
Less Common but Serious Side Effects
- Bleeding problems (nosebleeds, blood in urine or stool)
- Liver function problems
- Skin changes or peeling
- Mouth sores
Severe Reactions – Seek Immediate Help
- Severe chest pain
- Difficulty breathing
- Vision changes
- Fainting or irregular heartbeat
- Signs of allergic reaction (swelling of face/lips, breathing trouble)
Warning and Precaution
Who Should Avoid This Medication
- People with severe liver or kidney problems
- Patients with uncontrolled high blood pressure
- Pregnant women (can harm the unborn baby)
- Breastfeeding mothers may harm their babies.
Drug Interactions
- Avoid using with:
- Amiodarone
- Pimozide
- Haloperidol
- Sotalol
- Thioridazine
Inform your doctor about all medications you are taking.
Food & Lifestyle Considerations
- Avoid alcohol (may worsen side effects).
- Do not drive or operate machinery if you feel dizzy or tired.
- Avoid grapefruit juice, as it may interact with the drug.
Special Warnings
- Requires regular blood pressure monitoring.
- May require liver function tests during treatment.
Use effective birth control during treatment and for at least 1 month after stopping.
Patient Guidance
- Store in a cool, dry place away from sunlight.
- Keep out of reach of children.
- Take with a full glass of water.
- Take it at the same time daily for the best results.
- Do not share this medicine with anyone.
- Do not use after the expiry date.
Clinical Trial & Approvals
- Lenvatinib has been tested in large clinical trials for thyroid, liver, and kidney cancer.
- The SELECT trial (392 patients with thyroid cancer) significantly improved progression-free survival.
- The REFLECT trial (954 patients with liver cancer) showed similar survival benefits to sorafenib but with better tumor response.
- Lenvatinib is FDA-approved and included in NCCN treatment guidelines for relevant cancers.
References
MedlinePlus: Lenvatinib – Drug Information Click here
NCBI Bookshelf: Lenvatinib Summary: Comprehensive medical and clinical profile. Click here
DrugBank: Lenvatinib drug interactions, targets, and mechanisms. Click here
Medscape: Lenvima (Lenvatinib) pharmacology and usage. Click here
Drugs.com: Guidance on lenvatinib usage and risks. Click here
FAQ
What is Lenvat 10 mg used for?
What is Lenvatinib 10 mg used for?
How does Lenvat 10 mg work?
What are the side effects of Lenvatinib capsules?
Which cancers are treated with Lenvatinib?
How successful is Lenvatinib?
Does Lenvatinib shrink tumors?
How long can you take Lenvatinib?
Can Lenvat 10 mg capsule cause infertility?
Can Lenvat 10 mg capsule cause hair loss?
Can Lenvat 10 mg capsule cause heart problems?
Can Lenvat 10 mg capsule cause vision problems?
Can Lenvat 10 mg capsule be used in children?
Can I undergo tooth extraction while taking Lenvat 10 mg?
What should I do if I miss a dose of Lenvat 10 mg?
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Rosa Farrell –
It’s very effective for cancer. My husband take it